without a doubt. If you remember the scenes with "Charlie" where she offered to help her with her makeup and gave her emotional support over the tension between her and Charlie's mother, it clearly shows that, despite her ditzy personality, Rose put a lot into her relationships with the people she loved, and always wanted the best for them.
Dorothy would also have been a great grandmother since she was insightful and educated. We just never got to see her "in action."
Blanche? Too self centered, based on her interaction with two of her granddaughters, where she was worried about herself, instead of them.
Sophia? Too many mean remarks, and too many inaccurate urban legends that gave distorted impressions about the world. Not a good way to go when raising an impressionable child.